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Immunology

Page 1

Promiscuous gene expression

What is the main driver of Promiscuous Gene Expression (PGE) in the thymus?

Macrophage-1 antigen

What is the function of Macrophage-1 antigen (CR3)?

Damage-associated molecular pattern

What are DAMPs also known as?

Immunological synapse

What is the structure known as the central-SMAC composed of in an immunological synapse?

Interleukin-1 family

Which IL-1 family member is synthesized as a precursor protein and stored in the cytoplasm of cells of mesenchymal origin and epithelial cells?

Interleukin-1 family

Which cytokine is called an endogenous pyrogen due to its role in raising body temperature (fever)?

Interleukin-1 family

Which cytokines are the most studied members of the IL-1 family due to their strong proinflammatory effects?