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Genetics
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TOR1AIP1
What conditions have been linked to mutations in TOR1AIP1?
Diabetes and hypertension
Cancer and Alzheimer's disease
Muscular dystrophy and cardiomyopathy
Parkinson's disease and multiple sclerosis
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Why?
TOR1AIP1
What happens when TOR1AIP1 is deleted from mouse hepatocytes?
It leads to increased lipoprotein secretion
It causes liver cancer
It has no effect on the liver
It leads to non-alcoholic fatty liver disease and non-alcoholic steatohepatitis
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Why?
TOR1AIP1
What is the function of lamina associated polypeptide 1 (LAP1)?
It is involved in the synthesis of lipoproteins
It is a type I integral membrane protein
It is a cytoplasmic protein
It interacts with Torsin A and is necessary for the ATPase activity of Torsin A
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Why?
RNA world
What is the difference between RNA and DNA?
RNA has a different sugar molecule than DNA
RNA has a different number of strands than DNA
RNA has a different set of bases than DNA
RNA is more stable than DNA
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Meningioma
What is the most frequent genetic mutation involved in meningioma?
BRCA1
BRCA2
Neurofibromatosis 2 gene
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Why?
Life
What is the unit of heredity?
Cell
Gene
Protein
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Why?
Preimplantation genetic diagnosis
What is the term used to refer to the set of techniques for testing whether embryos have abnormal chromosomes' number?
Preimplantation genetic diagnosis (PGD)
Preimplantation genetic profiling
Aneuploidy screening
Oocyte selection
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Why?
Preimplantation genetic diagnosis
What was the world's first preimplantation genetic diagnosis (PGD) performed for?
Beta-thalassemia
Sickle-cell anemia
Duchenne's muscular dystrophy
X-linked disease
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Why?
Preimplantation genetic diagnosis
What is the main advantage of preimplantation genetic diagnosis (PGD) when used to screen for a specific genetic disease?
It increases the chances of successful pregnancy
It allows for sex selection
It helps diagnose late-onset diseases
It avoids selective abortion
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Why?
Neutral network (evolution)
What are neutral networks in a fitness landscape?
Sets of genes that have different functions
Sets of genes that are not connected by point mutations
Sets of genes that have equivalent function and are connected by point mutations
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